Silencing of the chromatin remodeler Mi-2β in keratinocytes triggers local skin inflammation. Regulatory T cells activated by the cytokine TSLP control the shift from local skin inflammation to systemic lethal disease.
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Pattarini, L., Soumelis, V. Keeping skin inflammation local. Nat Immunol 18, 250–251 (2017). https://doi.org/10.1038/ni.3687
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DOI: https://doi.org/10.1038/ni.3687
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