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Family ties among CNS macrophages

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Perivascular and subdural meningeal macrophages at the interface between the central nervous system and the periphery are self-renewing and arise from early embryonic precursors. Macrophages residing in the choroid plexus have dual origin, developing from circulating bone-marrow-derived monocytes and embryonic progenitors.

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Figure 1: Ontogeny of CNS macrophages.

Marina Corral Spence / Nature Publishing Group

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Authors and Affiliations

  1. Melanie Greter is with the Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland.,

    Melanie Greter

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  1. Melanie Greter
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Correspondence to Melanie Greter.

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Greter, M. Family ties among CNS macrophages. Nat Immunol 17, 742–743 (2016). https://doi.org/10.1038/ni.3490

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