Immune responses are characterized by the concerted actions of both effector mechanisms and regulatory mechanisms. Signaling via the transcription factor STAT1 downstream of receptors for interferons and interleukin 27 (IL-27) can suppress type 2 immune responses induced by group 2 innate lymphoid cells (ILCs).
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Stehle, C., Saikali, P. & Romagnani, C. Putting the brakes on ILC2 cells. Nat Immunol 17, 43–44 (2016). https://doi.org/10.1038/ni.3353
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DOI: https://doi.org/10.1038/ni.3353
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