Clusters of dermal dendritic cells and T cells are required for efficient activation of T cells in skin following hapten sensitization via a process dependent on interleukin 1α (IL-1α) and the chemokine CXCL2 produced by macrophages.
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Mueller, S. Skin DCs cluster for efficient T cell activation. Nat Immunol 15, 1004–1005 (2014). https://doi.org/10.1038/ni.3012
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DOI: https://doi.org/10.1038/ni.3012
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