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Fingerprinting Ikaros

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Zinc fingers 1 and 4 of Ikaros have unique functions in the selection of Ikaros target genes, lymphocyte development and the suppression of leukemogenesis.

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Figure 1: Distinct functions of Ikaros zinc fingers 1 and 4 in the development and transformation of lymphocytes.

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Correspondence to Fotini Gounari or Barbara L Kee.

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Gounari, F., Kee, B. Fingerprinting Ikaros. Nat Immunol 14, 1034–1035 (2013). https://doi.org/10.1038/ni.2709

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