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Solving the plot: early events are the key to diabetes intervention

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Type 1 diabetes is usually diagnosed after most insulin-producing islets of Langerhans have already been destroyed. However, magnetic resonance imaging can be used to predict the onset of type 1 diabetes, and a benign prognosis correlates with the presence of anti-inflammatory tissue-resident macrophages.

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Figure 1: The predictive power of MRI leads to the development of a prophylactic treatment for type 1 diabetes.

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Authors and Affiliations

  1. Alexander V. Chervonsky is in the Department of Pathology, The University of Chicago, Chicago, Illinois, USA.,

    Alexander V Chervonsky

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  1. Alexander V Chervonsky
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Correspondence to Alexander V Chervonsky.

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The author declares no competing financial interests.

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Chervonsky, A. Solving the plot: early events are the key to diabetes intervention. Nat Immunol 13, 311–312 (2012). https://doi.org/10.1038/ni.2259

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