Proinflammatory signaling by the interleukin 17 receptor requires the adaptor Act1. Two studies identify an additional function for Act1 and identify new participants that regulate the inflammatory effects of IL-17.
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May, M. IL-17R signaling: new players get in on the Act1. Nat Immunol 12, 813–815 (2011). https://doi.org/10.1038/ni.2093
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DOI: https://doi.org/10.1038/ni.2093
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