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NUR who? An orphan transcription factor holds promise for monomaniacs

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The generation of Ly6C− patrolling monocytes requires the transcription factor NR4A1 (Nur77). This finding provides insight into the development and function of these blood-resident cells.

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Figure 1: Monocytes and their potential derivatives.

Katie Vicari

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Authors and Affiliations

  1. Derek W. Cain is in the Department of Immunology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.,

    Derek W Cain

  2. Michael D. Gunn is in the Division of Cardiology and Department of Immunology, Duke University Medical Center, Durham, North Carolina, USA.,

    Michael D Gunn

Authors
  1. Derek W Cain
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  2. Michael D Gunn
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Correspondence to Michael D Gunn.

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The authors declare no competing financial interests.

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Cain, D., Gunn, M. NUR who? An orphan transcription factor holds promise for monomaniacs. Nat Immunol 12, 727–729 (2011). https://doi.org/10.1038/ni.2074

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