New studies employing high-throughput parallel sequencing have revealed WDR62 mutations in individuals with microcephaly associated with a broad range of malformations of cortical development. These findings establish that WDR62 acts as a molecular link between proliferation and migration in neurogenesis.
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Wollnik, B. A common mechanism for microcephaly. Nat Genet 42, 923–924 (2010). https://doi.org/10.1038/ng1110-923
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DOI: https://doi.org/10.1038/ng1110-923
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