Skip to main content
SpringerLink
Log in

Photoreceptors in evolution and disease

  • News & Views
  • Published:

From Nature Genetics

View current issue Submit your manuscript

A new study identifies the gene that, when mutated, causes autosomal recessive retinitis pigmentosa 25 (arRP25). The RP25 gene encodes an ortholog of Drosophila spacemaker (eyes shut), thus emphasizing common biological functions between Drosophila sensory systems and the human eye.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Figure 1: A comparison of Drosophila and human retinas.

References

  1. Daiger, S.P., Bowne, S.J. & Sullivan, L.S. Arch. Ophthalmol. 125, 151–158 (2007).

    Article  CAS  Google Scholar 

  2. Hartong, D.T., Berson, E.L. & Dryja, T.P. Lancet 368, 1795–1809 (2006).

    Article  CAS  Google Scholar 

  3. Abd El-Aziz, M.M. et al. Nat. Genet. 40, 1285–1287 (2008).

    Article  CAS  Google Scholar 

  4. Abd El-Aziz, M.M. et al. Ann. Hum. Genet. 71, 281–294 (2007).

    Article  CAS  Google Scholar 

  5. Barragan, I., Marcos, I., Borrego, S. & Antinolo, G. Int. J. Mol. Med. 16, 1163–1167 (2005).

    CAS  PubMed  Google Scholar 

  6. Khaliq, S. et al. Am. J. Hum. Genet. 65, 571–574 (1999).

    Article  CAS  Google Scholar 

  7. Ruiz, A., Borrego, S., Marcos, I. & Antinolo, G.A. Am. J. Hum. Genet. 62, 1452–1459 (1998).

    Article  CAS  Google Scholar 

  8. Abd El-Aziz, M.M. et al. Ann. Hum. Genet. 72, 463–477 (2008).

    Article  CAS  Google Scholar 

  9. Husain, N. et al. Dev. Cell 11, 483–493 (2006).

    Article  CAS  Google Scholar 

  10. Zelhof, A.C., Hardy, R.W., Becker, A. & Zuker, C.S. Nature 443, 696–699 (2006).

    Article  CAS  Google Scholar 

  11. Cook, B., Hardy, R.W., McConnaughey, W.B. & Zuker, C.S. Nature 452, 361–364 (2008).

    Article  CAS  Google Scholar 

  12. Maw, M.A. et al. Hum. Mol. Genet. 9, 27–34 (2000).

    Article  CAS  Google Scholar 

  13. Yang, Z. et al. J. Clin. Invest. 118, 2908–2916 (2008).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Boaz Cook is in the Department of Cell Biology, The Scripps Research Institute, La Jolla, California 92037, USA. bcook@scripps.edu,

    Boaz Cook

  2. Andrew C. Zelhof is in the Department of Biology, Indiana University, Bloomington, Indiana 47405, USA. azelhof@indiana.edu,

    Andrew C Zelhof

Authors
  1. Boaz Cook
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Andrew C Zelhof
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Cook, B., Zelhof, A. Photoreceptors in evolution and disease. Nat Genet 40, 1275–1276 (2008). https://doi.org/10.1038/ng1108-1275

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/ng1108-1275

  • Springer Nature America, Inc.

This article is cited by

Search

Navigation