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Rescuing distal crossovers

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Optimally positioned crossovers facilitate the proper segregation of chromosomes in meiosis. A new study in yeast implicates the spindle checkpoint in the rescue of crossovers that occur too distant from the centromere, possibly shedding light on the origins of nondisjunction in higher organisms.

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Figure 1: Crossovers facilitate segregation at meiosis I, but their efficiency depends on number and location.

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Authors and Affiliations

  1. Terry Hassold and Patricia Hunt are in the School of Molecular Biosciences, Washington State University, Pullman, Washington 99164, USA. terryhassold@wsu.edu,

    Terry Hassold & Patricia Hunt

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  1. Terry Hassold
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  2. Patricia Hunt
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Hassold, T., Hunt, P. Rescuing distal crossovers. Nat Genet 39, 1187–1188 (2007). https://doi.org/10.1038/ng1007-1187

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  • DOI: https://doi.org/10.1038/ng1007-1187

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