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Infectious diseases not immune to genome-wide association

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Two genome-wide association studies for meningococcal disease and tuberculosis identify new loci associated with susceptibility to these infectious diseases. They highlight a role for the acquired and innate immune systems in host control of several human pathogens and demonstrate that denser genotyping platforms and population-specific reference panels are necessary for genetic studies in African populations.

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Authors and Affiliations

  1. Paul I.W. de Bakker is at the Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.,

    Paul I W de Bakker

  2. Amalio Telenti is at the Institute of Microbiology, University Hospital Center, University of Lausanne, Lausanne, Switzerland.,

    Amalio Telenti

Authors
  1. Paul I W de Bakker
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  2. Amalio Telenti
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Correspondence to Paul I W de Bakker or Amalio Telenti.

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The authors declare no competing financial interests.

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de Bakker, P., Telenti, A. Infectious diseases not immune to genome-wide association. Nat Genet 42, 731–732 (2010). https://doi.org/10.1038/ng0910-731

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