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Testing for association between MeCP2 and the brahma-associated SWI/SNF chromatin-remodeling complex

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A Correspondence to this article was published on 01 September 2006

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Figure 1: MeCP2 neither copurifies nor cofractionates with the SWI/SNF complex.
Figure 2: MeCP2 is concentrated in condensed heterochromatin regions, whereas brm is not.

References

  1. Harikrishnan, K.N. et al. Nat. Genet. 37, 254–264 (2005).

    Article  CAS  Google Scholar 

  2. Klose, R.J. & Bird, A.P. J. Biol. Chem. 279, 46490–46496 (2004).

    Article  CAS  Google Scholar 

  3. Wang, W. Curr. Top. Microbiol. Immunol. 274, 143–169 (2003).

    CAS  PubMed  Google Scholar 

  4. Jones, P.L. et al. Nat. Genet. 19, 187–191 (1998).

    Article  CAS  Google Scholar 

  5. Nan, X., Tate, P., Li, E. & Bird, A. Mol. Cell. Biol. 16, 414–421 (1996).

    Article  CAS  Google Scholar 

  6. Reyes, J.C., Muchardt, C. & Yaniv, M. J. Cell Biol. 137, 263–274 (1997).

    Article  CAS  Google Scholar 

  7. Nan, X., Campoy, F.J. & Bird, A. Cell 88, 471–481 (1997).

    Article  CAS  Google Scholar 

  8. Muchardt, C. & Yaniv, M. EMBO J. 12, 4279–4290 (1993).

    Article  CAS  Google Scholar 

  9. Reyes, J.C. et al. EMBO J. 17, 6979–6991 (1998).

    Article  CAS  Google Scholar 

  10. Guy, J., Hendrich, B., Holmes, M., Martin, J.E. & Bird, A. Nat. Genet. 27, 322–326 (2001).

    Article  CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Laboratory of Genetics, National Institute on Aging, National Institutes of Health, 333 Cassell Drive, Suite 3000, Triad Technology Center, Baltimore, 21224, Maryland, USA

    Keping Hu & Weidong Wang

  2. Wellcome Trust Centre for Cell Biology, University of Edinburgh, The King's Buildings, Edinburgh, EH9 3JR, Scotland, UK

    Xinsheng Nan & Adrian Bird

Authors
  1. Keping Hu
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  2. Xinsheng Nan
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  3. Adrian Bird
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  4. Weidong Wang
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Supplementary information

Supplementary Fig. 1

MeCP2 purified from NIH3T3 cells has no stably associated proteins and does not co-immunoprecipitate with brahma and BRG1. (PDF 431 kb)

Supplementary Fig. 2

The brm antibody used in Harikrishnan's study reacts well with human brm but poorly with mouse brm. (PDF 135 kb)

Supplementary Fig. 3

MeCP2 immunoprecipitated from HeLa nuclear extract has no stably associated proteins, as revealed by Coomassie staining. (PDF 9 kb)

Supplementary Fig. 4

MeCP2 is enriched in condensed chromatin regions, whereas brm is not. (PDF 48 kb)

Supplementary Note (PDF 101 kb)

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Hu, K., Nan, X., Bird, A. et al. Testing for association between MeCP2 and the brahma-associated SWI/SNF chromatin-remodeling complex. Nat Genet 38, 962–964 (2006). https://doi.org/10.1038/ng0906-962

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