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Analysis of the nucleotide sequence of chromosome VI from Saccharomyces cerevisiae

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Abstract

The complete nucleotide sequence of Saccharomyces cerevisiae chromosome VI (270 kb) has revealed that it contains 129 predicted or known genes (300 bp or longer). Thirty–seven (28%) of which have been identified previously. Among the 92 novel genes, 39 are highly homologous to previously identified genes. Local sequence motifs were compared to active ARS regions and inactive loci with perfect ARS core sequences to examine the relationship between these motifs and ARS activity. Additional ARS sequences were predominantly observed in 3′ flanking sequences of active ARS loci.

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Authors and Affiliations

  1. Division of Human Genome Research, Tsukuba Life Science Center, The Institute of Physical and Chemical Research (RIKEN), 3-1-1 Koyadai, Tsukuba, Ibaraki, 305, Japan

    Yasufumi Murakami, Masanori Naitou, Hiroko Hagiwara, Masashi Ozawa, Syun-ichi Sasanuma, Motoe Sasanuma, Yukari Tsuchiya & Toshihiko Eki

  2. Graduate School of Science and Engineering, Saitama University, 255 Shimo-okubo, Urawa, Saitama, 338, Japan

    Hiroko Hagiwara & Takehiko Shibata

  3. Biodesign Research Group, The Institute of Physical and Chemical Research (RIKEN), 2-1 Hirosawa, Wako, Saitama, 351-01, Japan

    Takehiko Shibata

  4. Bioscience Research Laboratory, Fujiya, Co., 228 Soya, Hatano, Kanagawa, 257, Japan

    Masaaki Yamazaki & Hiroyuki Tashiro

  5. Gene Bank, Tsukuba Life Science Center, The Institute of Physical and Chemical Research (RIKEN), 3-1-1 Koyadai, Tsukuba, Ibaraki, 305, Japan

    Eiichi Soeda & Kazushige Yokoyama

Authors
  1. Yasufumi Murakami
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  2. Masanori Naitou
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  3. Hiroko Hagiwara
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  4. Takehiko Shibata
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  5. Masashi Ozawa
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  6. Syun-ichi Sasanuma
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  7. Motoe Sasanuma
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  8. Yukari Tsuchiya
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  9. Eiichi Soeda
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  10. Kazushige Yokoyama
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  11. Masaaki Yamazaki
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  12. Hiroyuki Tashiro
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  13. Toshihiko Eki
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Murakami, Y., Naitou, M., Hagiwara, H. et al. Analysis of the nucleotide sequence of chromosome VI from Saccharomyces cerevisiae. Nat Genet 10, 261–268 (1995). https://doi.org/10.1038/ng0795-261

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  • DOI: https://doi.org/10.1038/ng0795-261

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