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Coiled-coils and motile cilia

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Genetic mapping studies in dogs, mice, zebrafish and humans have identified two new genes required for the assembly of motile cilia. The resulting gene products, CCDC39 and CCDC40, may represent previously unidentified components of the dynein regulatory complex.

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Figure 1: Comparison of normal and CCDC39-deficient cilia.

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  1. Peter Satir is in the Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, New York, New York, USA.,

    Peter Satir

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  1. Peter Satir
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Correspondence to Peter Satir.

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The author declares no competing financial interests.

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Satir, P. Coiled-coils and motile cilia. Nat Genet 43, 10–11 (2011). https://doi.org/10.1038/ng0111-10

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