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Promoting transcription over long distances

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Promoters and enhancers have long been regarded as distinct elements, a notion that has been challenged more recently. Two new studies now identify promoters that function as long-range enhancers in vivo to regulate the transcription of distal genes.

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Figure 1: Promoters regulate distal gene transcription.

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Authors and Affiliations

  1. Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), Vienna, Austria

    Rui R Catarino, Christoph Neumayr & Alexander Stark

Authors
  1. Rui R Catarino
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  2. Christoph Neumayr
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  3. Alexander Stark
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Correspondence to Alexander Stark.

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The authors declare no competing financial interests.

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Catarino, R., Neumayr, C. & Stark, A. Promoting transcription over long distances. Nat Genet 49, 972–973 (2017). https://doi.org/10.1038/ng.3904

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