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SWI/SNF complex in cancer

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Four studies in this issue report new mechanisms underlying the function of the chromatin remodeling SWI/SNF complex in controlling gene expression and suppressing tumor development, providing valuable insights into the treatment of cancers harboring mutations in genes encoding SWI/SNF complex subunits.

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Figure 1: New remodeling mechanisms underline the tumor-suppressive function of the SWI/SNF complex.

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Authors and Affiliations

  1. Chao Lu and C. David Allis are in the Laboratory of Chromatin Biology and Epigenetics, Rockefeller University, New York, New York, USA.,

    Chao Lu & C David Allis

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  1. Chao Lu
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  2. C David Allis
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Correspondence to Chao Lu or C David Allis.

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Lu, C., Allis, C. SWI/SNF complex in cancer. Nat Genet 49, 178–179 (2017). https://doi.org/10.1038/ng.3779

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