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Connecting the regulatory genome

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Determining how the evolving genome-wide map of distal regulatory elements is connected with target genes has remained a significant challenge, despite progress in understanding chromatin architecture and regulation. A new study presents a computational approach for predicting distal element–gene interactions.

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Figure 1: Connecting distal elements with target genes.

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Authors and Affiliations

  1. John Stamatoyannopoulos is in the Departments of Genome Sciences and Medicine at the University of Washington and at the Altius Institute for Biomedical Sciences, Seattle, Washington, USA.,

    John Stamatoyannopoulos

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  1. John Stamatoyannopoulos
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Correspondence to John Stamatoyannopoulos.

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Stamatoyannopoulos, J. Connecting the regulatory genome. Nat Genet 48, 479–480 (2016). https://doi.org/10.1038/ng.3553

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