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From genomics to diagnostics of esophageal adenocarcinoma

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The genetic determinants of progression from premalignant Barrett's esophagus to esophageal adenocarcinoma are not known. A new study reports genomic sequence analyses of this progression and uses the insights gained to identify high-risk Barrett's esophagus in a new non-endoscopic test.

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Figure 1: Potential role for the Cytosponge in clinical care.

Debbie Maizels/Nature Publishing Group

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Authors and Affiliations

  1. Fred Hutchinson Cancer Research Center and the Department of Epidemiology, Thomas L. Vaughan is in the Cancer Epidemiology Program, University of Washington, Seattle, Washington, USA.,

    Thomas L Vaughan

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  1. Thomas L Vaughan
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Correspondence to Thomas L Vaughan.

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The author declares no competing financial interests.

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Vaughan, T. From genomics to diagnostics of esophageal adenocarcinoma. Nat Genet 46, 806–807 (2014). https://doi.org/10.1038/ng.3047

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