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Should cannabinoids be used as analgesics for neuropathic pain?

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References

  1. Rice ASC et al. (2007) Cannabinoids and analgesia with special reference to neuropathic pain. In Systematic Reviews and Meta-Analyses in Pain, 233–246 (Eds McQuay HJ. et al.) Seattle: IASP Press

    Google Scholar 

  2. Svendsen KB et al. (2004) Does the cannabinoid dronabinol reduce central pain in multiple sclerosis? Randomised double blind placebo controlled crossover trial. BMJ 329: 253–257

    Article  CAS  Google Scholar 

  3. Rog DJ et al. (2005) Randomized, controlled trial of cannabis-based medicine in central pain in multiple sclerosis. Neurology 65: 812–819

    Article  Google Scholar 

  4. Rice ASC (2008) Cannabinoids for neuropathic pain? Where next? Neuropathic Pain 11: 3–6 [http://www.neupsig.org]

    Google Scholar 

  5. Frank B et al. (2008) Comparison of analgesic effects and patient tolerability of nabilone and dihydrocodeine for chronic neuropathic pain: randomised, crossover, double blind study. BMJ 336: 199–201

    Article  CAS  Google Scholar 

  6. Nurmikko TJ et al. (2007) Sativex successfully treats neuropathic pain characterised by allodynia: a randomised, double-blind, placebo-controlled clinical trial. Pain 133: 210–220

    Article  CAS  Google Scholar 

  7. Abrams DI et al. (2007) Cannabis in painful HIV-associated sensory neuropathy: a randomized placebo-controlled trial. Neurology 68: 515–521

    Article  CAS  Google Scholar 

  8. Ellis RJ et al. (2008) Smoked medicinal cannabis for neuropathic pain in HIV: a randomized, crossover clinical trial. Neuropsychopharmacology [10.1038/npp.2008.120]

  9. Wang T et al. (2008) Adverse effects of medical cannabinoids: a systematic review. CMAJ 178: 1669–1678

    Article  Google Scholar 

  10. Semple DM et al. (2005) Cannabis as a risk factor for psychosis: systematic review. J Psychopharmacol 19: 187–194

    Article  Google Scholar 

  11. Moore TH et al. (2007) Cannabis use and risk of psychotic or affective mental health outcomes: a systematic review. Lancet 370: 319–328

    Article  Google Scholar 

  12. Zammit S et al. (2002) Self reported cannabis use as a risk factor for schizophrenia in Swedish conscripts of 1969: historical cohort study. BMJ 325: 1199–2005

    Article  Google Scholar 

  13. Henquet C et al. (2005) Prospective cohort study of cannabis use, predisposition for psychosis, and psychotic symptoms in young people. BMJ 330: 11

    Article  Google Scholar 

  14. Caspi A et al. (2005) Moderation of the effect of adolescent-onset cannabis use on adult psychosis by a functional polymorphism in the catechol-O-methyltransferase gene: longitudinal evidence of a gene X environment interaction. Biol Psychiatry 57: 1117–1127

    Article  CAS  Google Scholar 

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Author notes

  1. Department of Anaesthetics, Pain Medicine and Intensive Care, Imperial College London, Chelsea and Westminster Hospital Campus, 369 Fulham Road, London SW10 9NH, UK a.rice@imperial.ac.uk

Authors and Affiliations

  1. ASC Rice is Professor of Pain Research at Imperial College London, London, UK.,

    Andrew SC Rice

Authors
  1. Andrew SC Rice
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Competing interests

ASC Rice is a patent holder/applicant with Imperial Innovations, has received a grant or research support from Pfizer and Spiniflex, and is a consultant for Pfizer, BTG, GlaxoSmithKline, Eisai, Allergan, Solvay, Organon (Schering–Plough) and Lectus Therapeutics. He is also named as inventor on a palmitoylethanolamide-related patent (WO 2005/079771).

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Rice, A. Should cannabinoids be used as analgesics for neuropathic pain?. Nat Rev Neurol 4, 654–655 (2008). https://doi.org/10.1038/ncpneuro0949

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  • DOI: https://doi.org/10.1038/ncpneuro0949

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