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Complete pain relief: potential problems and diagnostic solutions

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References

  1. Gureje O et al. (1998) Persistent pain and well-being: a World Health Organization study in primary care. JAMA 280: 147–151

    Article  CAS  Google Scholar 

  2. Frymoyer JW and Cats-Baril WL (1991) An overview of the incidences and costs of low back pain. Orthop Clin North Am 22: 263–271

    CAS  Google Scholar 

  3. Ekman M et al. (2005) The economic cost of low back pain in Sweden in 2001. Acta Orthop 76: 275–284

    Article  Google Scholar 

  4. Brown DC et al. (2005) Physiologic and antinociceptive effects of intrathecal resiniferatoxin in a canine bone cancer model. Anesthesiology 103: 1052–1059

    Article  Google Scholar 

  5. Benoliel R et al. (1999) Actions of intrathecal diphtheria toxin-substance P fusion protein on models of persistent pain. Pain 79: 243–253

    Article  CAS  Google Scholar 

  6. Mantyh PW et al. (1997) Inhibition of hyperalgesia by ablation of lamina I spinal neurons expressing the substance P receptor. Science 278: 275–279

    Article  CAS  Google Scholar 

  7. Vulchanova L et al. (2001) Cytotoxic targeting of isolectin IB4-binding sensory neurons. Neuroscience 108: 143–155

    Article  CAS  Google Scholar 

  8. Cox JJ et al. (2006) An SCN9A channelopathy causes congenital inability to experience pain. Nature 444: 894–898

    Article  CAS  Google Scholar 

  9. Nagasako EM et al. (2003) Congenital insensitivity to pain: an update. Pain 101: 213–219

    Article  Google Scholar 

  10. Metzl JD (2005) Anabolic steroids and the pediatric community. Pediatrics 116: 1542

    Article  Google Scholar 

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Correspondence to Michael J Iadarola.

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Mannes, A., Iadarola, M. Complete pain relief: potential problems and diagnostic solutions. Nat Rev Neurol 3, 648–649 (2007). https://doi.org/10.1038/ncpneuro0660

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