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Can add-on pioglitazone prevent recurrent stroke in patients with type 2 diabetes?

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From Nature Clinical Practice Neurology

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References

  1. Dormandy JA et al. (2005) Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial. Lancet 366: 1279–1289

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  2. Nissen SE and Wolski K (2007) Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes. N Engl J Med 356: 2457–2471

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  3. Pfutzner A et al. (2006) Pioglitazone: an antidiabetic drug with cardiovascular therapeutic effects. Expert Rev Cardiovasc Ther 4: 445–459

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  4. Insulin Resistance Intervention after Stroke Trial [www.iristrial.org]

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Acknowledgements

The synopsis was written by Martina Habeck, Associate Editor, Nature Clinical Practice.

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Author notes

  1. Cleveland Clinic Foundation, S91, 9500 Euclid Avenue, Cleveland, OH 44195, USA katzani@ccf.org

Authors and Affiliations

  1. I Katzan is a Vascular Neurologist at Cleveland Clinic and Case Western Reserve University's Center for Health Care Research and Policy at MetroHealth Medical Center in Cleveland, OH, USA.,

    Irene Katzan

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  1. Irene Katzan
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The author declares no competing financial interests.

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Katzan, I. Can add-on pioglitazone prevent recurrent stroke in patients with type 2 diabetes?. Nat Rev Neurol 3, 486–487 (2007). https://doi.org/10.1038/ncpneuro0562

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  • DOI: https://doi.org/10.1038/ncpneuro0562

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