References
Giovannoni G et al. (2002) Neutralising antibodies to interferon beta during the treatment of multiple sclerosis. J Neurol Neurosurg Psychiatry 73: 465–469
The IFNB Multiple Sclerosis Study Group and the University of British Columbia MS/MRI Analysis Group (1996) Neutralizing antibodies during treatment of multiple sclerosis with interferon beta-1b: experience during the first three years. Neurology 47: 889–894
PRISMS (Prevention of Relapses and Disability by Interferon-β-1a Subcutaneously in Multiple Sclerosis) Study Group and the University of British Columbia MS/MRI Analysis Group (2001) PRISMS-4: long-term efficacy of interferon-β-1a in relapsing MS. Neurology 56: 1628–1636
Francis GS et al. (2005) Interferon β-1a in MS: results following development of neutralizing antibodies in PRISMS. Neurology 65: 48–55
Panitch H et al. (2005) Benefits of high-dose, high-frequency interferon beta-1a in relapsing-remitting multiple sclerosis are sustained to 16 months: final comparative results of the EVIDENCE trial. J Neurol Sci 239: 67–74
Rice GPB et al. (1999) The evolution of neutralizing antibodies in multiple sclerosis patients treated with interferon beta-1b. Neurology 52: 1277–1279
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The synopsis was written by Carol Lovegrove, Freelance Medical Writer.
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Oger, J., Gibbs, E. Should neutralizing antibodies be monitored during interferon-β treatment for multiple sclerosis?. Nat Rev Neurol 2, 76–77 (2006). https://doi.org/10.1038/ncpneuro0098
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DOI: https://doi.org/10.1038/ncpneuro0098
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