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Leptin and colorectal cancer: an undefined link

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From Nature Clinical Practice Gastroenterology & Hepatology

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References

  1. Mohamed-Ali V et al. (1998) Adipose tissue as an endocrine and paracrine organ. Int J Obes Relat Metab Disord 22: 1145–1158

    Article  CAS  Google Scholar 

  2. Friedman JM (1998) Leptin, leptin receptors, and the control of body weight. Nutr Rev 56: 38–46

    Article  Google Scholar 

  3. Considine RV et al. (1996) The hypothalamic leptin receptor in humans: identification of incidental sequence polymorphisms and absence of the db/db mouse and fa/fa rat mutations. Diabetes 45: 992–994

    Article  Google Scholar 

  4. Baumgartner RN et al. (1999) Age-related changes in sex hormones affect the sex difference in serum leptin independently of changes in body fat. Metabolism 48: 378–384

    Article  CAS  Google Scholar 

  5. Hardwick JC et al. (2001) Leptin is a growth factor for colonic epithelial cells. Gastroenterology 121: 79–90

    Article  CAS  Google Scholar 

  6. Slattery ML et al. (1997) Energy balance and colon cancer—beyond physical activity. Cancer Res 57: 75–80

    CAS  PubMed  Google Scholar 

  7. Slattery ML et al. (2003) Body mass index and colon cancer: an evaluation of the modifying effects of estrogen (United States). Cancer Causes Control 14: 75–84

    Article  CAS  Google Scholar 

  8. Fain JN et al. (2001) Stimulation of leptin release by arachidonic acid and prostaglandin E(2) in adipose tissue from obese humans. Metabolism 50: 921–928

    Article  CAS  Google Scholar 

  9. Stattin P et al. (2004) Obesity and colon cancer: does leptin provide a link? Int J Cancer 109: 149–152

    Article  CAS  Google Scholar 

  10. Stattin P et al. (2003) Plasma leptin and colorectal cancer risk: a prospective study in Northern Sweden. Oncol Rep 10: 2015–2021

    PubMed  Google Scholar 

Download references

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Authors and Affiliations

  1. and RK Wolff is an Associate Professor in the Department of Internal Medicine at the University of Utah, ML Slattery is a Professor of Epidemiology, Salt Lake City, UT, USA.,

    Martha L Slattery & Roger K Wolff

Authors
  1. Martha L Slattery
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  2. Roger K Wolff
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Correspondence to Martha L Slattery.

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The authors declare no competing financial interests.

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Slattery, M., Wolff, R. Leptin and colorectal cancer: an undefined link. Nat Rev Gastroenterol Hepatol 4, 118–119 (2007). https://doi.org/10.1038/ncpgasthep0743

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  • DOI: https://doi.org/10.1038/ncpgasthep0743

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