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Implications of the universal definition of myocardial infarction

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From Nature Clinical Practice Cardiovascular Medicine

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Abstract

The original WHO definition of myocardial infarction (MI) was revised in 2000 and further refined in 2007. Central to the new universal definition of MI was the use of the highly sensitive and specific biomarker troponin. In the investigation reviewed in this commentary, Hochholzer et al. showed that acute and long-term postinfarction prognosis and mortality were adversely affected when patients met the newly revised criteria for acute MI.

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References

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Authors and Affiliations

  1. JS Alpert is a Professor of Medicine at the University of Arizona College of Medicine, Tucson, AZ, USA,,

    Joseph S Alpert

  2. K Thygesen is a Professor in the Departments of Medicine and Cardiology at Aarhus University Hospital, Aarhus, Denmark,

    Kristian Thygesen

  3. HD White is Director of Coronary Care and Cardiovascular Research in the Green Lane Cardiovascular Service at Auckland City Hospital, and an Honorary Clinical Professor of Medicine at the University of Auckland, Auckland, New Zealand, and,

    Harvey D White

  4. AS Jaffe is a Professor of Medicine and Consultant in Cardiology and Laboratory Medicine and Pathology at the Mayo Clinic, Rochester, MN, USA.,

    Allan S Jaffe

Authors
  1. Joseph S Alpert
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  2. Kristian Thygesen
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  3. Harvey D White
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  4. Allan S Jaffe
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Corresponding author

Correspondence to Joseph S Alpert.

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Competing interests

K Thygesen and AS Jaffe have acted as Consultants for Roche Diagnostics and Siemens. The other authors declared no competing interests.

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Alpert, J., Thygesen, K., White, H. et al. Implications of the universal definition of myocardial infarction. Nat Rev Cardiol 5, 678–679 (2008). https://doi.org/10.1038/ncpcardio1329

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  • DOI: https://doi.org/10.1038/ncpcardio1329

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