References
Yusuf S et al. for the Clopidogrel in Unstable Angina to Prevent Recurrent Events Trial Investigators (2001) Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation. N Engl J Med 345: 494–502
Sabatine MS et al. for the CLARITY-TIMI 28 Investigators (2005) Addition of clopidogrel to aspirin and fibrinolytic therapy for myocardial infarction with ST-segment elevation. N Engl J Med 352: 1179–1189
Bhatt DL (2006) Can clopidogrel and aspirin lower mortality in patients with acute myocardial infarction? Nat Clin Pract Cardiovasc Med 3: 182–183
Bhatt DL and Topol EJ (2003) Scientific and therapeutic advances in antiplatelet therapy. Nat Rev Drug Discov 2: 15–28
Bhatt DL (2007) Intensifying platelet inhibition—navigating between Scylla and Charybdis. N Engl J Med 357: 2078–2081
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The synopsis was written by Alexandra King, Associate Editor, Nature Clinical Practice.
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DL Bhatt has received research funding (directly to the Cleveland Clinic) from Bristol-Myers Squibb, Eisai, Ethicon, Heartscape Technologies, Sanofi-Aventis, and The Medicines Company. He has received payments for Speaker's Bureau appointments from Bristol-Myers Squibb, Sanofi-Aventis, and The Medicines Company. He has received honoraria from AstraZeneca, Bristol-Myers Squibb, Centocor, Eisai, Eli Lilly, GlaxoSmithKline, Millennium Pharmaceuticals, ParinGenix, PDL BioPharma, Sanofi-Aventis, Schering Plough, The Medicines Company, and TNS Healthcare. He has also acted as a Consultant or Advisory Board member for Astellas Pharma, AstraZeneca, Bayer, Bristol-Myers Squibb, Cardax Pharmaceuticals, Centocor, Cogentus Pharmaceuticals, Daiichi-Sankyo, Eisai, Eli Lilly, GlaxoSmithKline, Johnson & Johnson, Medtronic, Millennium Pharmaceuticals, Molecular Insight Pharmaceuticals, Ortho-McNeil Pharmaceutical, Otsuka, ParinGenix, PDL BioPharma, Philips Medical, Portola Pharmaceuticals, Sanofi-Aventis, Schering Plough, Scios, The Medicines Company, TNS Healthcare, and Vertex Pharmaceuticals.
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Bhatt, D. Is prasugrel superior to clopidogrel for patients with acute coronary syndromes undergoing PCI?. Nat Rev Cardiol 5, 252–253 (2008). https://doi.org/10.1038/ncpcardio1164
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DOI: https://doi.org/10.1038/ncpcardio1164
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