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A bacterial copper metallothionein

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Metallothioneins sequester cadmium and surplus atoms of copper and zinc to prevent aberrant metal-catalyzed reactions. The identification of a 'cryptic' copper metallothionein in the bacterium that causes tuberculosis suggests that bacterial metallothioneins may be more widespread than previously suspected.

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Figure 1: Copper-handling proteins of Mycobacterium tuberculosis.

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Robinson, N. A bacterial copper metallothionein. Nat Chem Biol 4, 582–583 (2008). https://doi.org/10.1038/nchembio1008-582

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