Sensors and reporters are among the most exciting tools used in cell biology. Now, they are increasingly used in developmental biology and medicine because they allow us to spy on events in living cells and organisms, including humans, in real time and with high spatial resolution. Herein, we discuss multiple design options for fluorescent sensors and reporters as well as strategies to improve their properties and increase development.
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Lemke, E., Schultz, C. Principles for designing fluorescent sensors and reporters. Nat Chem Biol 7, 480–483 (2011). https://doi.org/10.1038/nchembio.620
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DOI: https://doi.org/10.1038/nchembio.620
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