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Principles of a switch

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Lambda's 'genetic switch' responds in a dramatic all-or-none fashion to an environmental signal, activating transcription of certain genes as it turns off others. The switch illustrates principal features of many biological regulatory processes.

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Figure 1: The lambda switch.
Figure 2: Examples of regulatory protein actions in eukaryotes.

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Correspondence to Mark Ptashne.

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Ptashne, M. Principles of a switch. Nat Chem Biol 7, 484–487 (2011). https://doi.org/10.1038/nchembio.611

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