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Biomaterials

Metabolites empowering minerals

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Amorphous mineral phases play important roles in the skeletons of many organisms, but the molecular basis for species-specific control is still under debate. The demonstration that energy-rich metabolites such as phosphoenolpyruvate stabilize amorphous calcium carbonate (ACC) in crayfish inspires speculation about calcium minerals in emerging metabolisms.

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Figure 1: Hypothetical rudimentary metabolism involving Pi, PEP and 3PG and ACC.

References

  1. Lowenstam, H.A. Science 211, 1126–1131 (1981).

    Article  CAS  Google Scholar 

  2. Addadi, L., Raz, S. & Weiner, S. Adv. Mater. 15, 959–970 (2003).

    Article  CAS  Google Scholar 

  3. Beniash, E. et al. Proc. R. Soc. Lond. B 264, 461–465 (1997).

    Article  CAS  Google Scholar 

  4. Weiner, S. J. Struct. Biol. 163, 229–234 (2008).

    Article  CAS  Google Scholar 

  5. Radha, A.V., Forbes, T.Z., Killian, C.E., Gilbert, P.U. & Navrotsky, A. Proc. Natl. Acad. Sci. USA 107, 16438–16443 (2010).

    Article  CAS  Google Scholar 

  6. Sato, A. et al. Nat. Chem. Biol. 7, 197–199 (2011).

    Article  CAS  Google Scholar 

  7. Lippmann, F. Sedimentary Carbonate Minerals (Springer, Heidelberg, 1973).

    Book  Google Scholar 

  8. Cornish-Bowden, A. (ed.). New Beer in an Old Bottle: Eduard Buchner and the Growth of Biochemical Knowledge (Universitat de València, València, Spain, 1997).

    Google Scholar 

  9. Horowitz, N.H. Proc. Natl. Acad. Sci. USA 31, 153–157 (1945).

    Article  CAS  Google Scholar 

  10. Oparin, A.I. The Origin of Life on Earth. Trans. Ann Synge (Academic, New York, 1957).

    Google Scholar 

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Correspondence to Ingrid M Weiss.

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Weiss, I. Metabolites empowering minerals. Nat Chem Biol 7, 192–193 (2011). https://doi.org/10.1038/nchembio.550

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