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Tapping into personalized chemistry

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By integrating metagenomics, spectroscopy and synthetic biology, the individualized chemistry of small reef-dwelling organisms and their associated microbiota can be characterized in exquisite detail, unlocking a wealth of structural diversity for the development of new drugs.

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Figure 1: A bioactivity-driven drug-discovery approach to exploiting the full diversity of complex ecosystems.

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Authors and Affiliations

  1. Jack R. Davison and Carole A. Bewley are in the Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health, Bethesda, Maryland, USA

    Jack R Davison & Carole A Bewley

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  1. Jack R Davison
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  2. Carole A Bewley
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Correspondence to Carole A Bewley.

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The authors declare no competing financial interests.

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Davison, J., Bewley, C. Tapping into personalized chemistry. Nat Chem Biol 14, 108–109 (2018). https://doi.org/10.1038/nchembio.2560

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