Skip to main content
Log in

Membrane fusion

A new role for lipid domains?

  • News & Views
  • Published:

From Nature Chemical Biology

View current issue Submit your manuscript

Boundaries between ordered and disordered membrane domains may be the site of HIV fusion protein insertion into its target membrane.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Figure 1: How HIV fusion peptide interacts with domain boundaries.

References

  1. Südhof, T.C. & Rothman, J.E. Science 323, 474–477 (2009).

    Article  Google Scholar 

  2. Carr, C.M. & Kim, P.S. Cell 73, 823–832 (1993).

    Article  CAS  Google Scholar 

  3. Skehel, J.J. & Wiley, D.C. Annu. Rev. Biochem. 69, 531–569 (2000).

    Article  CAS  Google Scholar 

  4. Kielian, M. & Rey, F.A. Nat. Rev. Microbiol. 4, 67–76 (2006).

    Article  CAS  Google Scholar 

  5. Yang, S.-T., Kiessling, V., Simmons, J.A., White, J.M. & Tamm, L.K. Nat. Chem. Biol. 11, 424–431 (2015).

    Article  CAS  Google Scholar 

  6. Ono, A. & Freed, E.O. Proc. Natl. Acad. Sci. USA 98, 13925–13930 (2001).

    Article  CAS  Google Scholar 

  7. Toulmay, A. & Prinz, W.A. J. Cell Biol. 202, 35–44 (2013).

    Article  CAS  Google Scholar 

  8. LaRocca, T.J. et al. PLoS Pathog. 9, e1003353 (2013).

    Article  CAS  Google Scholar 

  9. Zech, T. et al. EMBO J. 28, 466–476 (2009).

    Article  CAS  Google Scholar 

  10. Harder, T., Rentero, C., Zech, T. & Gaus, K. Curr. Opin. Immunol. 19, 470–475 (2007).

    Article  CAS  Google Scholar 

  11. Mahammad, S., Dinic, J., Adler, J. & Parmryd, I. Biochim. Biophys. Acta 1801, 625–634 (2010).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Erwin London.

Ethics declarations

Competing interests

The author declares no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

London, E. A new role for lipid domains?. Nat Chem Biol 11, 383–384 (2015). https://doi.org/10.1038/nchembio.1812

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nchembio.1812

  • Springer Nature America, Inc.

This article is cited by

Navigation