Heterodimerization of G protein–coupled receptors can lead to the activation of intracellular pathways that are not triggered by either of the individual receptors. This property may lead to the development of new therapeutic approaches showcasing increased efficiency and selectivity.
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Parmentier, M. Heterodimer-specific signaling. Nat Chem Biol 11, 244–245 (2015). https://doi.org/10.1038/nchembio.1772
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DOI: https://doi.org/10.1038/nchembio.1772
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