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Osmotic stress

Is CoQ a membrane stabilizer?

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Coenzyme Q10 is an essential lipid in aerobic respiratory metabolism and a membrane antioxidant. A new function is revealed for CoQ; as a membrane-stabilizing agent that enhances resistance of bacterial cell and liposome membranes to salt stress.

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Figure 1: Osmotic stress response and membrane stability.

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Author notes

  1. Catherine F Clarke, Amy C Rowat and James W Gober: All authors are at the University of California–Los Angeles, Los Angeles, California, USA.

Authors and Affiliations

  1. Catherine F. Clarke and James W. Gober are in the Department of Chemistry and Biochemistry and the Molecular Biology Institute.,

    Catherine F Clarke & James W Gober

  2. Amy C. Rowat is in the Department of Integrative Biology and Physiology and the Molecular Biology Institute.,

    Amy C Rowat

Authors
  1. Catherine F Clarke
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  2. Amy C Rowat
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  3. James W Gober
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Corresponding author

Correspondence to Catherine F Clarke.

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The authors declare no competing financial interests.

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Clarke, C., Rowat, A. & Gober, J. Is CoQ a membrane stabilizer?. Nat Chem Biol 10, 242–243 (2014). https://doi.org/10.1038/nchembio.1478

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