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Regenerative medicine

Of fish and men

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Stem cell therapeutics hold great promise, but obtaining optimal cell populations for transplantation remains a major challenge. High-throughput screens of zebrafish embryonic cells have enabled identification of small molecules that can direct the fate of pluripotent stem cells toward tissue-specific progenitors with high therapeutic potential.

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Figure 1: Screening for small molecules to direct the differentiation of iPSCs for therapeutic applications.

Katie Vicari

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Authors and Affiliations

  1. Thomas A. Rando is in the Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California, USA.,

    Thomas A Rando

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  1. Thomas A Rando
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Correspondence to Thomas A Rando.

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The authors declare no competing financial interests.

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Rando, T. Of fish and men. Nat Chem Biol 10, 91–92 (2014). https://doi.org/10.1038/nchembio.1449

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