Skip to main content
SpringerLink
Log in

Metalloenzymes

Put a ring on it

  • News & Views
  • Published:

From Nature Chemical Biology

View current issue Submit your manuscript

The structure of a bacterial methane oxidation complex reveals how protein-protein interactions can mediate coupling of proton, electron and substrate delivery to a metal active site.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Figure 1: Protein-protein interactions in the MMOH–MMOB methane oxidation complex modulate access to the active site.

References

  1. Jiang, H. et al. Biochem. Eng. J. 49, 277–288 (2010).

    Article  CAS  Google Scholar 

  2. Culpepper, M.A. & Rosenzweig, A.C. Crit. Rev. Biochem. Mol. Biol. 47, 483–492 (2012).

    Article  CAS  Google Scholar 

  3. Tinberg, C.E. & Lippard, S.J. Acc. Chem. Res. 44, 280–288 (2011).

    Article  CAS  Google Scholar 

  4. Colby, J. & Dalton, H. Biochem. J. 171, 461–468 (1978).

    Article  CAS  Google Scholar 

  5. Rosenzweig, A.C., Frederick, C.A., Lippard, S.J. & Nordlund, P. Nature 366, 537–543 (1993).

    Article  CAS  Google Scholar 

  6. Walters, K.J., Gassner, G.T., Lippard, S.J. & Wagner, G. Proc. Natl. Acad. Sci. USA 96, 7877–7882 (1999).

    Article  CAS  Google Scholar 

  7. Lee, S.J., McCormick, M.S., Lippard, S.J. & Cho, U.S. Nature 494, 380–384 (2013).

    Article  CAS  Google Scholar 

  8. Wallar, B.J. & Lipscomb, J.D. Chem. Rev. 96, 2625–2658 (1996).

    Article  CAS  Google Scholar 

  9. Sazinsky, M.H., Dunten, P.W., McCormick, M.S., DiDonato, A. & Lippard, S.J. Biochemistry 45, 15392–15404 (2006).

    Article  CAS  Google Scholar 

  10. Bailey, L.J., McCoy, J.G., Phillips, G.N. & Fox, B.G. Proc. Natl. Acad. Sci. USA 105, 19194–19198 (2008).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Amy C. Rosenzweig is at the Department of Molecular Biosciences and the Department of Chemistry, Northwestern University, Evanston, Illinois, USA.,

    Amy C Rosenzweig

Authors
  1. Amy C Rosenzweig
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Amy C Rosenzweig.

Ethics declarations

Competing interests

The author declares no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Rosenzweig, A. Put a ring on it. Nat Chem Biol 9, 220–221 (2013). https://doi.org/10.1038/nchembio.1208

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nchembio.1208

  • Springer Nature America, Inc.

Search

Navigation