The aggregation of proteins into fibrils plays a crucial role in neurological conditions such as Parkinson's disease. Further insight into fibril formation has now been gained that reveals the effect of hydrophobic surfaces, including air.
This is a preview of subscription content, log in via an institution to check access.
References
Chiti, F. & Dobson, C. M. Annu. Rev. Biochem. 75, 333–366 (2006).
Hamley, I. W. Angew. Chem. Int. Ed. 46, 8128–8147 (2007).
Knowles, T. P. J. et al. Science 326, 1533–1537 (2009).
Pronchik, J., He, X., Giurleo, J. T. & Talaga, D. S. J. Am. Chem. Soc. 132, 9797–9803 (2010).
Cabaleiro-Lago, C., Lynch, I., Dawson, K. A. & Linse, S. Langmuir 26, 3453–3461 (2010).
Chromy, B. A. et al. Biochemistry 42, 12749–12760 (2003).
Soreghan, B., Kosmoski, J. & Glabe, C. G. J. Biol. Chem. 269, 28551–28554 (1994).
Kim, W. K. & Hecht, M. H. Proc. Natl Acad. Sci. USA 103, 15824–15829 (2006).
Petkova, A. T. et al. Science 307, 262–265 (2005).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Hamley, I. Interface influence. Nature Chem 2, 707–708 (2010). https://doi.org/10.1038/nchem.816
Issue Date:
DOI: https://doi.org/10.1038/nchem.816
- Springer Nature Limited