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Mass spectrometry

Tracking molecular mobility

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By studying non-covalent assemblies in the gas phase, it is possible to examine the mobility of the components within a single complex — rather than between different complexes — using hydrogen/deuterium exchange reactions.

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Figure 1: Dynamics of a crown ether/oligolysine complex in the gas phase.

References

  1. Schneider, H.-J. Angew. Chem. Int. Ed. 48, 3924–3977 (2009).

    Article  CAS  Google Scholar 

  2. Weimann, D. P., Winkler, H. D. F., Falenski, J. A., Koksch, B. & Schalley, C. A. Nature Chem. 1, 573–577 10.1038/nchem.352(2009).

    Article  CAS  Google Scholar 

  3. Loo, J. A. Int. J. Mass Spectrom. 200, 175–186 (2000).

    Article  CAS  Google Scholar 

  4. McCullough, B. J. & Gaskell, S. J. Comb. Chem. High T. Scr. 12, 203–211 (2009).

    CAS  Google Scholar 

  5. Bohrer, B. C., Merenbloom, S. I., Koeniger, S. L., Hilderbrand, A. E. & Clemmer, D. E. Annu. Rev. Anal. Chem. 1, 293–327 (2008).

    Article  CAS  Google Scholar 

  6. Benesch, J. L. P., Ruotolo, B. T., Simmons, D. A. & Robinson, C. V. Chem. Rev. 107, 3544–3567 (2007).

    Article  CAS  PubMed  Google Scholar 

  7. Wyttenbach, T. & Bowers, M. T. J. Am. Soc. Mass Spectrom. 10, 9–14 (1999).

    Article  CAS  Google Scholar 

  8. Campbell, S., Rodgers, M. T., Marzluff, E. M. & Beauchamp, J. L. J. Am. Chem. Soc. 117, 12840–12854 (1995).

    Article  CAS  Google Scholar 

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Brodbelt, J. Tracking molecular mobility. Nature Chem 1, 526–527 (2009). https://doi.org/10.1038/nchem.382

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