Strategies for making sequence-controlled polymers in the laboratory are really quite primitive in comparison with those used in nature. By combining concepts from natural systems and synthetic polymer chemistry, it has now been shown that DNA codes can be translated into non-nucleic-acid polymers with defined sequences.
References
Niu, J., Hili, R. & Liu, D. R. Nature Chem. 5, 282–292 10.1038/nchem.1577(2013).
McKee, M. L. et al. Angew. Chem. Int. Ed. 49, 7948–7951 (2010).
He, Y. & Liu, D. R. J. Am. Chem. Soc. 133, 9972–9975 (2008).
Hili, R., Niu, J. & Liu, D. R. J. Am. Chem. Soc. 135, 98–101 (2013).
Pfeifer, S., Zarafshani, Z., Badi, N. & Lutz, J.-F. J. Am. Chem. Soc. 131, 9195–9197 (2009).
Pfeifer, S. & Lutz, J.-F. J. Am. Chem. Soc. 129, 9542–9543 (2007).
Hibi, Y., Ouchi, M. & Sawamoto, M. Angew. Chem. Int. Ed. 50, 7434–7437 (2011).
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O'Reilly, R. Not lost in translation. Nature Chem 5, 252–253 (2013). https://doi.org/10.1038/nchem.1603
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DOI: https://doi.org/10.1038/nchem.1603
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