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Site-selective reactions

Remodelling by diversity and design

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Bioactive molecules frequently contain several very similarly reactive functional groups and it can thus be difficult to cause one to react selectively. Now, two separate studies present complementary approaches to this desirable goal.

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Figure 1: Two complementary approaches to the design of site-selective reactions.

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Authors and Affiliations

  1. Pamela Tadross and Eric Jacobsen are in the Department of Chemistry and Chemical Biology at Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138, USA,

    Pamela M. Tadross & Eric N. Jacobsen

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  1. Pamela M. Tadross
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  2. Eric N. Jacobsen
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Correspondence to Eric N. Jacobsen.

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Tadross, P., Jacobsen, E. Remodelling by diversity and design. Nature Chem 4, 963–965 (2012). https://doi.org/10.1038/nchem.1509

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