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Anthrax receptors position the spindle

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Spindle orientation plays a pivotal role in tissue morphogenesis. An asymmetric anthrax receptor cap is revealed to promote activation of a formin to orient the spindle along the planar cell polarity (PCP) axis in zebrafish dorsal epiblast cells.

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Figure 1: Polarity at different scales.
Figure 2: Possible mechanisms for spindle orientation and centring.

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Authors and Affiliations

  1. Nicolas Minc and Matthieu Piel are at Institut Curie, UMR 144 CNRS/IC, 26 rue d'Ulm, 75248 Paris Cedex 05, France,

    Nicolas Minc & Matthieu Piel

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  1. Nicolas Minc
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  2. Matthieu Piel
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Correspondence to Nicolas Minc or Matthieu Piel.

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The authors declare no competing financial interests.

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Minc, N., Piel, M. Anthrax receptors position the spindle. Nat Cell Biol 15, 11–13 (2013). https://doi.org/10.1038/ncb2664

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