Skip to main content
Log in

PARtners for endocytosis

  • News & Views
  • Published:

From Nature Cell Biology

View current issue Submit your manuscript

The evolutionarily conserved PAR3–PAR6–aPKC–Cdc42 complex has a well-established role in cell polarity. The exact job of PAR proteins in polarity is not known, but the finding that they affect endocytosis casts new light on their function.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Figure 1: Role of anterior PAR proteins in endocytosis.
Figure 2: A model for the role of anterior PARs in polarity establishment.

References

  1. Kemphues, K. J., Priess, J. R., Morton, D. G. & Cheng, N. S. Cell 52, 311–320 (1988).

    Article  CAS  Google Scholar 

  2. Balklava, Z., Pant, S., Fares, H. & Grant, B. D. Nature Cell Biol. 9, 1066–1073 (2007).

    Article  CAS  Google Scholar 

  3. Kaksonen, M., Toret, C. P. & Drubin, D. G. Nature Rev. Mol. Cell Biol. 7, 404–414 (2006).

    Article  CAS  Google Scholar 

  4. Motegi, F. & Sugimoto, A. Nature Cell Biol. 8, 978–985 (2006).

    Article  CAS  Google Scholar 

  5. Munro, E., Nance, J. & Priess, J. R. Dev. Cell 7, 413–424 (2004).

    Article  CAS  Google Scholar 

  6. Schonegg, S. & Hyman, A. A. Development 133, 3507–3516 (2006).

    Article  CAS  Google Scholar 

  7. Nishimura, T. & Kaibuchi, K. Dev. Cell 13, 15–28 (2007).

    Article  CAS  Google Scholar 

  8. Suzuki, A. & Ohno, S. J. Cell Sci. 119, 979–987 (2006).

    Article  CAS  Google Scholar 

  9. Andrews, R. & Ahringer, J. PLoS ONE 2, e493 (2007).

    Article  Google Scholar 

  10. Macara, I. G. & Spang, A. Cell 125, 419–421 (2006).

    Article  CAS  Google Scholar 

  11. Kroschewski, R., Hall, A. & Mellman, I. Nature Cell Biol. 1, 8–13 (1999).

    Article  CAS  Google Scholar 

  12. Lu, H. & Bilder, D. Nature Cell Biol. 7, 1232–1239 (2005).

    Article  Google Scholar 

  13. Pelissier, A., Chauvin, J. P. & Lecuit, T. Curr. Biol. 13, 1848–1857 (2003).

    Article  CAS  Google Scholar 

  14. Marco, E., Wedlich-Soldner, R., Li, R., Altschuler, S. J. & Wu, L. F. Cell 129, 411 (2007).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Wissler, F., Labouesse, M. PARtners for endocytosis. Nat Cell Biol 9, 1027–1029 (2007). https://doi.org/10.1038/ncb0907-1027

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/ncb0907-1027

  • Springer Nature Limited

This article is cited by

Navigation