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Hold on tightly, let go lightly: myosin functions at adherens junctions

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Adherens junctions, the sites of cadherin-dependent cell–cell adhesion, are also important for dynamic tension sensing, force transduction and signalling. Different myosin motors contribute to adherens junction assembly and versatility in distinct ways.

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Figure 1: Adherens junctions may be functionally analogous to the kinetochore–sister chromatid complex.

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Authors and Affiliations

  1. Joshua C. Sandquist is in the Department of Zoology, University of Wisconsin-Madison, 1117 West Johnson Street, Madison WI 53706, USA. jsandquist@wisc.edu,

    Joshua C. Sandquist

  2. William M. Bement is in the Department of Zoology and the Laboratory of Molecular Biology, University of Wisconsin-Madison, 1117 West Johnson Street. Madison WI 53706, USA.,

    William M. Bement

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  1. Joshua C. Sandquist
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  2. William M. Bement
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Sandquist, J., Bement, W. Hold on tightly, let go lightly: myosin functions at adherens junctions. Nat Cell Biol 12, 633–635 (2010). https://doi.org/10.1038/ncb0710-633

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