Precise spatial regulation of mRNA remodelling is crucial for proper gene expression. One way this is accomplished is through activation of the DEAD-box helicase Dbp5 at the cytoplasmic fibrils of the nuclear-pore complex, by the nucleoporin Gle1 and the soluble inositol polyphosphate InsP6.
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Cole, C., Scarcelli, J. Unravelling mRNA export. Nat Cell Biol 8, 645–647 (2006). https://doi.org/10.1038/ncb0706-645
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DOI: https://doi.org/10.1038/ncb0706-645
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