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Monopolar attachment by Polo

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A distinguishing feature of meiosis is a reductional division where homologous chromosomes — rather than sister chromatids — are pulled to opposite poles. Polo-like kinase (Plk), a prominent regulator of mitotic progression in Saccharomyces cerevisiae, is also crucial in regulating chromosome and chromatid separation during meiosis.

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Figure 1: Proposed roles of the budding yeast Cdc5 polo-like kinase during meiosis I.

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Watanabe, Y. Monopolar attachment by Polo. Nat Cell Biol 5, 379–382 (2003). https://doi.org/10.1038/ncb0503-379

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