Despite being largely a post-mitotic tissue, adult skeletal muscle exhibits a remarkable capacity for regeneration. A new study has shown that cells derived from mural cells (pericytes) from blood vessels in postnatal human skeletal muscle contribute to robust skeletal muscle regeneration after intra-arterial delivery into a dystrophic mouse model.
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Morgan, J., Muntoni, F. Mural cells paint a new picture of muscle stem cells. Nat Cell Biol 9, 249–251 (2007). https://doi.org/10.1038/ncb0307-249
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DOI: https://doi.org/10.1038/ncb0307-249
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