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Drug Development: The role of innovation in drug development

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References

  1. Human disease—From genetic causes to biochemical effects. Proceedings of the Roche Symposium “The Genetic Basis of Human Disease”, October 2–3, 1996, Basel. Drews, J. and Ryser, S. (eds.) Ex Libris Roche 9. Blackwell Science, Berlin.

  2. Lifton, R. Human disease—From genetic causes to biochemical effects. Proceedings of the Roche Symposium “The Genetic Basis of Human Disease”, October 2–3, 1996, Basel. Drews, J. and Ryser, S. (eds.) Ex Libris Roche 9. Blackwell Science, Berlin.

  3. Weber, W. 1997. pp. 10–11 in Pharmacogenetics. Oxford Univ. Press, New York and Oxford.

    Google Scholar 

  4. Ohsako, S. and Deguchi, T. 1990. J. Biol. Chem. 265: 4630–4634.

    CAS  PubMed  Google Scholar 

  5. Weber, W. 1997. pp. 12–13 in Pharmacogenetics. Oxford Univ. Press, New York and Oxford.

    Google Scholar 

  6. Mossinghoff, G.J. 1995. Drug Info. J. 29: 1077–1090.

    Article  Google Scholar 

  7. Drews, J. and Ryser, S. 1997. Drug Discovery Today 2: 365–372.

    Article  Google Scholar 

  8. It is obvious that these constraints are entirely dependent on a set of financial assumptions relating to costs, sales and discount rates for R&D expenditures. If these assumptions are modified, if for instance the discount rates after launch are lowered from 14% to 8% or if only out of pocket expenses are taken into account and opportunity costs altogether neglected, the picture brightens considerably. Eventually, such changes may have to be made.

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Authors and Affiliations

  1. president of global research and Stefan Ryser is chief of international research staff, Hoffmann-La Roche, CH-4002, Basel, Switzerland

    Jürgen Drews & Stefan Ryser

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  1. Jürgen Drews
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  2. Stefan Ryser
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Drews, J., Ryser, S. Drug Development: The role of innovation in drug development. Nat Biotechnol 15, 1318–1319 (1997). https://doi.org/10.1038/nbt1297-1318

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