Complete maps of DNA methylation in human cells provide insight into the epigenetic regulation of pluripotency.
References
Lister, R. et al. Nature advance online publication, 10.1038/nature08514 (14 October 2009).
Dolinoy, D.C. & Jirtle, R.L. Environ. Mol. Mutagen. 49, 4–8 (2008).
Takahashi, K. & Yamanaka, S. Cell 126, 663–676 (2006).
Rollins, R.A. et al. Genome Res. 16, 157–163 (2006).
Thomson, J.A. et al. Science 282, 1145–1147 (1998).
Nichols, W.W. et al. Science 196, 60–63 (1977).
Lister, R. et al. Cell 133, 523–536 (2008).
Lander, E.S. et al. Nature 409, 860–921 (2001).
Ramsahoye, B.H. et al. Proc. Natl. Acad. Sci. USA 97, 5237–5242 (2000).
Jia, D., Jurkowska, R.Z., Zhang, X., Jeltsch, A. & Cheng, X. Nature 449, 248–251 (2007).
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Costello, J., Krzywinski, M. & Marra, M. A first look at entire human methylomes. Nat Biotechnol 27, 1130–1132 (2009). https://doi.org/10.1038/nbt1209-1130
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DOI: https://doi.org/10.1038/nbt1209-1130
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