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Cancer and complement

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A component of the complement system promotes tumor growth by activating myeloid-derived suppressor cells.

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Figure 1: Multiple pro-inflammatory mediators in the tumor microenvironment increase the accumulation of MDS cells and enhance their immunosuppressive activity.

Katie Ris-Vicari

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Authors and Affiliations

  1. Suzanne Ostrand-Rosenberg is in the Department of Biological Sciences, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, Maryland 21250, USA. srosenbe@umbc.edu,

    Suzanne Ostrand-Rosenberg

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  1. Suzanne Ostrand-Rosenberg
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Ostrand-Rosenberg, S. Cancer and complement. Nat Biotechnol 26, 1348–1349 (2008). https://doi.org/10.1038/nbt1208-1348

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