Combining microdroplet PCR with flow-cell technologies provides a novel approach for sequencing thousands of genomic targets.
References
Tewhey, R. et al. Nat. Biotechnol. 27, 1025–1031 (2009).
Sjoblom, T. et al. Science 314, 268–274 (2006).
Hodges, E. et al. Nat. Genet. 39, 1522–1527 (2007).
Albert, T.J. et al. Nat. Methods 4, 903–905 (2007).
Turner, E.H. et al. Nat. Methods 6, 315–316 (2009).
Gnirke, A. et al. Nat. Biotechnol. 27, 182–189 (2009).
Ng, S.B. et al. Nature 461, 272–276 (2009).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Kirkness, E. Targeted sequencing with microfluidics. Nat Biotechnol 27, 998–999 (2009). https://doi.org/10.1038/nbt1109-998
Issue Date:
DOI: https://doi.org/10.1038/nbt1109-998
- Springer Nature America, Inc.
This article is cited by
-
Culture and chemical-induced fusion of tobacco mesophyll protoplasts in a microfluidic device
Microfluidics and Nanofluidics (2011)
-
Mutation screening in 86 known X-linked mental retardation genes by droplet-based multiplex PCR and massive parallel sequencing
The HUGO Journal (2009)